Formulation of an effective mosquito-repellent topical product from lemongrass oil

Phytomedicine. 2002 Apr;9(3):259-62. doi: 10.1078/0944-7113-00120.


Ointment and cream formulations of lemongrass oil in different classes of base and the oil in liquid paraffin solution have been evaluated for mosquito repellency in a topical application. Mosquito repellency was tested by determining the bite-deterrence of product samples applied on an experimental bird's skin against a 2-day starved culture of Aedes aegypti L. mosquitoes. The 1%v/v solution and 15%v/w cream and ointment preparations of the oil exhibited > or =50% repellency lasting 2-3 h, which may be attributed to citral, a major oil constituent. This activity was comparable to that of a commercial mosquito repellent. Base properties of the lemongrass oil formulations influenced their effectiveness. The oil demonstrated efficacy from the different bases in the order of hydrophilic base > emulsion base > oleaginous base.

Publication types

  • Evaluation Study

MeSH terms

  • Administration, Cutaneous
  • Aedes / drug effects*
  • Animals
  • Chemistry, Pharmaceutical
  • Cymbopogon*
  • Insect Repellents / administration & dosage
  • Insect Repellents / pharmacology*
  • Ointments
  • Paraffin
  • Phytotherapy*
  • Plant Oils / administration & dosage
  • Plant Oils / pharmacology*


  • Insect Repellents
  • Ointments
  • Plant Oils
  • Paraffin