Theoretical and practical aspects of fast gas chromatography and method translation

J Chromatogr Sci. 2002 May-Jun;40(5):234-47. doi: 10.1093/chromsci/40.5.234.

Abstract

Interest in the development and implementation of fast gas chromatography (GC) methods continues to increase. Fast GC method development and validation can be simplified and more successful if a few key theoretical and practical concepts are kept in mind. Key concepts such as speed-optimized flow rate, optimal temperature-program rate, sample capacity, "cut the column", and principles of method translation are discussed.