Blood lead concentrations and iron deficiency in Canadian aboriginal infants

Sci Total Environ. 2002 Apr 22;289(1-3):255-60. doi: 10.1016/s0048-9697(01)01052-x.

Abstract

Aboriginal Cree infants living in northern Quebec who were 9 months of age were screened for anemia, iron deficiency and elevated blood lead concentrations. Of the 314 infants who were eligible to participate, 274 (87.3%) were screened for anemia, 186 had blood lead concentration measured and 141 of the latter group had iron status determined. The median blood lead concentration was 0.08 micromol/l (range 0.01-1.00 micromol/l). The 25, 50 and 75 percentiles for blood lead concentration were 0.05, 0.08 and 0.12 micromol/l, respectively. The prevalence of elevated blood lead concentrations (> 0.48 micromol/l) was 2.7% (95% Cl 0.36-5.0). Among infants who had blood lead measured, the prevalence of anemia (hemoglobin < 110 g/l) was 25.0% and 7.9% of infants had iron-deficiency anemia (hemoglobin < 110 g/l and serum ferritin < 10 microg/l). Anemic infants had a higher mean geometric blood lead concentration than did babies without anemia (0.11 micromol/l vs. 0.07 micromol/l, P = 0.003). Likewise, infants with iron-deficiency anemia had a significantly higher mean geometric blood lead concentration than infants without iron deficiency anemia (0.16 micromol/l vs. 0.07 micromol/l, P = 0.001). There was a significant negative correlation between blood lead and hemoglobin concentrations (r = -0.203, P = 0.006) and between blood lead and serum ferritin concentrations (r = -0.245, P = 0.003). Infants who were fed traditional food (fish, fowl and game) did not have a significantly different mean geometric blood lead concentration, hemoglobin concentration or serum ferritin concentration than infants who did not eat traditional food. Few infants (5.3%) ate traditional food daily.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anemia, Iron-Deficiency / epidemiology*
  • Anemia, Iron-Deficiency / ethnology
  • Animals
  • Canada / epidemiology
  • Diet
  • Environmental Exposure
  • Female
  • Fishes
  • Hemoglobins / analysis
  • Humans
  • Indians, North American*
  • Infant
  • Infant Welfare*
  • Iron / blood*
  • Lead / blood*
  • Male
  • Prevalence

Substances

  • Hemoglobins
  • Lead
  • Iron