The Diversity of Acetylated Proteins

Genome Biol. 2002;3(5):reviews0006. doi: 10.1186/gb-2002-3-5-reviews0006. Epub 2002 Apr 30.

Abstract

Acetylation of proteins, either on various amino-terminal residues or on the epsilon-amino group of lysine residues, is catalyzed by a wide range of acetyltransferases. Amino-terminal acetylation occurs on the bulk of eukaryotic proteins and on regulatory peptides, whereas lysine acetylation occurs at different positions on a variety of proteins, including histones, transcription factors, nuclear import factors, and alpha-tubulin.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Acetylation
  • Acetyltransferases / metabolism
  • Animals
  • Bacterial Proteins / metabolism
  • Eukaryotic Cells / chemistry
  • Eukaryotic Cells / metabolism
  • Genetic Variation*
  • Humans
  • Lysine / metabolism
  • Peptides / metabolism
  • Protein Processing, Post-Translational / genetics*
  • Proteins / metabolism

Substances

  • Bacterial Proteins
  • Peptides
  • Proteins
  • Acetyltransferases
  • Lysine