Nanaomycins, new antibiotics produced by a strain of Streptomyces. III. A new component, nanaomycin C, and biological activities of nanaomycin derivatives

J Antibiot (Tokyo). 1975 Dec;28(12):925-30. doi: 10.7164/antibiotics.28.925.

Abstract

A new component, nanaomycin C, has been isolated from culture medium of Streptomyces rosa var. notoensis, which had been found to produce nanaomycins A and B. Nanaomycin C is an amide of nanaomycin A. Biological activities of nanaomycin C and several derivatives of nanaomycin A are also shown. Acetylnanaomycin A exhibits as strong activities against Gram-positive bacteria, fungi and Mycoplasma gallisepticum as nanaomycin A.

MeSH terms

  • Anti-Bacterial Agents* / isolation & purification
  • Anti-Bacterial Agents* / pharmacology
  • Antifungal Agents / pharmacology
  • Enterobacteriaceae / drug effects
  • Mycoplasma / drug effects
  • Quinones / isolation & purification
  • Quinones / pharmacology
  • Staphylococcus aureus / drug effects
  • Streptomyces / metabolism*
  • Trichophyton / drug effects

Substances

  • Anti-Bacterial Agents
  • Antifungal Agents
  • Quinones