Diffuse esophageal leiomyomatosis with localized dense eosinophilic infiltration

Dis Esophagus. 2002;15(1):85-7. doi: 10.1046/j.1442-2050.2002.00239.x.


Diffuse esophageal leiomyomatosis is a rare cause of dysphagia. There is frequently a chronic inflammatory infiltrate, but here we present the first reported case in association with a dense infiltration of eosinophils and mast cells confined to the affected muscularis propria. This was successfully managed by long esophageal myotomy, with resolution of dysphagia and no symptomatic recurrence after 3 years.

Publication types

  • Case Reports

MeSH terms

  • Biopsy, Needle
  • Deglutition Disorders / diagnosis
  • Endosonography
  • Eosinophilia / pathology*
  • Esophageal Neoplasms / diagnosis
  • Esophageal Neoplasms / pathology*
  • Esophageal Neoplasms / surgery
  • Esophagoscopy
  • Follow-Up Studies
  • Humans
  • Leiomyomatosis / diagnosis
  • Leiomyomatosis / pathology*
  • Leiomyomatosis / surgery
  • Male
  • Middle Aged
  • Treatment Outcome