Large giant cell reparative granuloma of the petrous bone--case report

Neurol Med Chir (Tokyo). 2002 May;42(5):232-6. doi: 10.2176/nmc.42.232.


A 41-year-old man presented with a large mass bulging over the suprazygomatic temporal region. Neuroradiological examination showed that the huge extra-axial mass with osteolytic character originated from the upper surface of the petrous bone. Preoperative obliteration of the feeding arteries with super-selective intravascular embolization was helpful for the total removal of the tumor. Histological examination revealed that the tumor consisted of massive fibrohistiocytic proliferation with numerous heavily hemosiderin-laden macrophages and numerous multinucleated giant cells. The most probable diagnosis was giant cell reparative granuloma. Therefore, no postoperative irradiation or other adjuvant therapy was given.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Craniotomy
  • Embolization, Therapeutic
  • Granuloma, Giant Cell / diagnosis*
  • Granuloma, Giant Cell / therapy
  • Humans
  • Magnetic Resonance Imaging*
  • Male
  • Petrous Bone / diagnostic imaging*
  • Petrous Bone / pathology*
  • Tomography, X-Ray Computed*