Chronic hepatitis C and autoimmune cholangitis: a case study and literature review

Dig Dis Sci. 2002 Jun;47(6):1224-9. doi: 10.1023/a:1015341625934.


We present a case of a chronic hepatitis C with damage of bile ducts resembling primary biliary cirrhosis. The immunological profile (negative antimitochondrial antibodies and positive anti-nuclear antibody) was characteristic of the autoimmune cholangitis. One year of treatment with ursodeoxycholic acid returned the liver tests to the normal range but the liver lesions remained unchanged.

Publication types

  • Case Reports

MeSH terms

  • Autoimmune Diseases / pathology*
  • Cholagogues and Choleretics / therapeutic use
  • Cholangitis / pathology*
  • Female
  • Hepatitis C, Chronic / drug therapy
  • Hepatitis C, Chronic / pathology*
  • Humans
  • Liver / pathology*
  • Middle Aged
  • Mitochondria, Liver / immunology
  • Ursodeoxycholic Acid / therapeutic use


  • Cholagogues and Choleretics
  • Ursodeoxycholic Acid