Antithrombin activity of medicinal plants from central Florida

Natalya Chistokhodova; Chi Nguyen; Tony Calvino; Ioulia Kachirskaia; Glenn Cunningham; D Howard Miles

doi:10.1016/s0378-8741(02)00097-1

Antithrombin activity of medicinal plants from central Florida

J Ethnopharmacol. 2002 Jul;81(2):277-80. doi: 10.1016/s0378-8741(02)00097-1.

Authors

Natalya Chistokhodova¹, Chi Nguyen, Tony Calvino, Ioulia Kachirskaia, Glenn Cunningham, D Howard Miles

Affiliation

¹ Department of Chemistry, University of Central Florida, Orlando, FL 32816, USA.

PMID: 12065163
DOI: 10.1016/s0378-8741(02)00097-1

Abstract

A chromogenic bioassay was utilized to determine the antithrombin activity of methylene chloride and methanol extracts prepared from 30 plants of central Florida. Extracts of Ardisia crenata, Tetrapanax papyriferus, Lagerstroemia indica, Callistemon lanceolatus, Antigonon Leptopus, Magnolia virginiana, and Myrica cerifera demonstrated activity of 80% or higher in this bioassay system.

MeSH terms

Fibrinolytic Agents / isolation & purification
Fibrinolytic Agents / pharmacology*
Fibrinolytic Agents / therapeutic use
Florida
Magnolia
Plant Extracts / isolation & purification
Plant Extracts / pharmacology
Plant Extracts / therapeutic use
Plants, Medicinal*
Thrombin / antagonists & inhibitors*
Thrombin / metabolism

Substances

Fibrinolytic Agents
Plant Extracts
Thrombin