Abstract
Lymphokines such as migration inhibitory factor and type II interferon were released into the circulation of tuberculin-sensitive mice after iv injection of old tuberculin. Daily administration of such sera into the tumor sites of mice given implants of sarcoma MC-36 markedly suppressed tumor growth.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Female
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Hypersensitivity, Delayed / immunology
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Lymphokines / therapeutic use*
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Mice
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Mice, Inbred C3H
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Monocytes / cytology
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Neoplasm Transplantation
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Sarcoma, Experimental / immunology
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Sarcoma, Experimental / pathology
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Sarcoma, Experimental / therapy*