[Pulmonary hypertension and obesity]

Rev Pneumol Clin. 2002 Apr;58(2):104-10.
[Article in French]


Obesity is a morbid condition with hemodynamic consequences affecting the systemic and pulmonary circulations leading to a risk of pulmonary hypertension. Data in the literature do not argue in favor of a direct relationship between pulmonary hypertension and obesity. These two conditions appear to be two distinct entities, the different co-morbidities observed in obesity favoring pulmonary hypertension. Certain co-morbidities, for instance use of anorexic agents, exhibit a clear relationship with pulmonary hypertension. There is also a possible relationship with left ventricular failure, hypoxemia, and other respiratory disorders (including obstructive sleep apnea), hypothyroidism, and thomboembolism.

Publication types

  • Review

MeSH terms

  • Aminorex / adverse effects
  • Aminorex / analogs & derivatives*
  • Fenfluramine / adverse effects
  • Fenfluramine / analogs & derivatives
  • Hemodynamics
  • Humans
  • Hypertension, Pulmonary / etiology*
  • Hypothyroidism / etiology
  • Hypoxia / etiology
  • Obesity / complications*
  • Obesity / physiopathology
  • Risk Factors
  • Severity of Illness Index
  • Sleep Apnea Syndromes / etiology


  • Fenfluramine
  • Aminorex
  • aminorex fumarate