Risk and responsibility: ethics, Grimes v Kennedy Krieger, and public health research involving children

Am J Public Health. 2002 Jul;92(7):1073-6. doi: 10.2105/ajph.92.7.1073.


The legal case of Grimes v. Kennedy Krieger Institute, Inc, has raised concerns in the public health research community regarding the acceptable level of risk in research involving children, parental authority for informed consent, and exploitation of research subjects for the benefit of public health. We provide an overview of the case and discuss the impact of the court's decision and its possible effect on future research protection policies and practices.

Publication types

  • Legal Case

MeSH terms

  • Child
  • Child Advocacy / legislation & jurisprudence*
  • Clinical Trials as Topic / legislation & jurisprudence*
  • Ethics*
  • Human Experimentation / legislation & jurisprudence*
  • Humans
  • Lead / adverse effects
  • Lead / analysis
  • Maryland
  • Moral Obligations
  • Public Health / legislation & jurisprudence*
  • Public Health / standards
  • Public Housing
  • Risk
  • Social Responsibility
  • Third-Party Consent / legislation & jurisprudence*


  • Lead