The BRCA1 suppressor hypothesis: an explanation for the tissue-specific tumor development in BRCA1 patients

Cancer Cell. 2002 Mar;1(2):129-32. doi: 10.1016/s1535-6108(02)00041-7.
No abstract available

Publication types

  • Letter

MeSH terms

  • BRCA1 Protein / genetics*
  • BRCA1 Protein / metabolism*
  • Breast Neoplasms / genetics
  • Breast Neoplasms / metabolism*
  • Breast Neoplasms / therapy
  • Cell Division
  • Cell Survival
  • Female
  • Genes, BRCA1*
  • Heterozygote
  • Humans
  • Models, Biological*
  • Mutation / genetics
  • Organ Specificity
  • Ovarian Neoplasms / genetics
  • Ovarian Neoplasms / metabolism*
  • Ovarian Neoplasms / therapy

Substances

  • BRCA1 Protein