Juvenile human T lymphotropic virus type 1-associated myelopathy

Clin Infect Dis. 2002 Jul 15;35(2):201-4. doi: 10.1086/341251. Epub 2002 Jun 24.

Abstract

We report the cases of 5 adolescents with human T lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis, acquired in all but 1 case from the mother. The first symptom in all patients was difficulty in running, which was present for many years before the final diagnosis was made. Follow-up showed an indolent progression, regardless of treatment strategy.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Breast Feeding / adverse effects
  • Child
  • Disease Progression
  • Female
  • HTLV-I Antibodies / blood
  • HTLV-I Antibodies / cerebrospinal fluid
  • Human T-lymphotropic virus 1* / immunology
  • Human T-lymphotropic virus 1* / isolation & purification
  • Humans
  • Infectious Disease Transmission, Vertical
  • Male
  • Paraparesis, Tropical Spastic / blood
  • Paraparesis, Tropical Spastic / cerebrospinal fluid
  • Paraparesis, Tropical Spastic / diagnosis*
  • Paraparesis, Tropical Spastic / drug therapy
  • Treatment Failure

Substances

  • HTLV-I Antibodies