On differences between immunity and immunological memory

Curr Opin Immunol. 2002 Aug;14(4):523-36. doi: 10.1016/s0952-7915(02)00367-9.


The evolutionary benefits of immunological memory are important: whereas antibodies can be transmitted to offspring by their mother and thereby benefit the species, T cell memory may function to help the individual combat persistent infection in peripheral tissues. Although experimental immunological memory is largely maintained antigen-independently, protective immunity is antigen-dependent.

Publication types

  • Review

MeSH terms

  • Animals
  • Antibody Formation*
  • Antigens / immunology
  • B-Lymphocytes / immunology
  • Cattle
  • Humans
  • Immunity, Cellular*
  • Immunity, Maternally-Acquired
  • Immunologic Memory*
  • Immunologic Tests
  • Mice
  • T-Lymphocytes / immunology
  • Terminology as Topic
  • Virus Diseases / immunology


  • Antigens