Fluid management and postoperative respiratory disturbances in patients with transthoracic esophagectomy for carcinoma

J Clin Anesth. 2002 Jun;14(4):252-6. doi: 10.1016/s0952-8180(02)00352-5.


Study objective: To investigate whether intraoperative fluid management contributes to postoperative respiratory disturbances in esophagectomy for carcinoma.

Design: Retrospective study.

Setting: Operating room and postanesthetic care unit of the cancer center.

Patients: From 1997 to 2000, 112 ASA physical status I, II, and III patients with primary carcinoma of the esophagus undergoing transthoracic esophagectomy.

Interventions and measurements: As of 1998, we altered fluid management during esophagectomy to save intraoperative fluid administration. Then, we investigated postoperative respiratory disturbances after esophagectomy in the period from 1998 to 2000 (late period) compared with the period from 1997 to 1998 (early period). We also investigated the relationship between perioperative risk factors and postoperative respiratory disturbances. The need for frequent (>10) bronchoscopic suctioning of sputum during postoperative period, the need for tracheostomy, and failure in the removal of endotracheal tube (ETT) (extubation) on the first postoperative day (1 POD) were investigated for respiratory disturbances after surgery.

Main results: Intraoperative volume balance decreased more so in the late period compared with early period (p < 0.0,001). The need for tracheostomy, bronchoscopic suctioning, and extubation failure on 1 POD were more frequent in the early period than in the late period (p = 0.0083, p = 0.0319, and p = 0.0024, respectively). The hospital recovery period after surgery was shortened during the late period (p = 0.032). Intraoperative volume balance affected the need for tracheostomy and frequent bronchoscopy postoperatively.

Conclusions: Careful intraoperative fluid administration may decrease postoperative respiratory disturbances.

MeSH terms

  • Adult
  • Aged
  • Bronchoscopy
  • Carcinoma / surgery*
  • Esophageal Neoplasms / surgery*
  • Esophagectomy*
  • Esophagoplasty
  • Female
  • Fluid Therapy*
  • Humans
  • Intraoperative Care*
  • Logistic Models
  • Male
  • Middle Aged
  • Odds Ratio
  • Postoperative Complications / prevention & control*
  • Respiration Disorders / etiology*
  • Respiration Disorders / prevention & control
  • Respiration Disorders / therapy
  • Retrospective Studies
  • Risk Factors
  • Suction
  • Tracheostomy