Abstract
Several recent studies have provided evidence that good diabetes control is important to prevent diabetic retinopathy. However, some groups of patients develop diabetic retinopathy despite good control and others escape retinopathy despite poor control. This suggests the role of genetic factors in susceptibility to retinopathy. This article reviews the role of genetic factors in determining diabetic retinopathy.
MeSH terms
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Aldehyde Reductase / genetics
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Diabetes Mellitus, Type 2 / genetics
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Diabetic Retinopathy / genetics*
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Endothelial Growth Factors / genetics
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Genes
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HLA Antigens / genetics
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Humans
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Lymphokines / genetics
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Nitric Oxide Synthase / genetics
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Peptidyl-Dipeptidase A / genetics
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Receptor for Advanced Glycation End Products
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Receptors, Immunologic / genetics
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Vascular Endothelial Growth Factor A
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Vascular Endothelial Growth Factors
Substances
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Endothelial Growth Factors
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HLA Antigens
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Lymphokines
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Receptor for Advanced Glycation End Products
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Receptors, Immunologic
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Vascular Endothelial Growth Factor A
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Vascular Endothelial Growth Factors
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Aldehyde Reductase
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Nitric Oxide Synthase
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Peptidyl-Dipeptidase A