Bronchial artery embolization for hemoptysis in young patients with cystic fibrosis

Radiology. 2002 Jul;224(1):124-30. doi: 10.1148/radiol.2241010654.


Purpose: To review the authors' 15-year experience with bronchial artery embolization (BAE) for treatment of hemoptysis in young patients with cystic fibrosis.

Materials and methods: By searching the 1985-1999 radiology database, the authors identified 23 young patients who had been referred to the radiology department for angiography. Twenty of these patients underwent BAE. The 23 medical records were retrospectively reviewed with regard to embolization agents used, embolization success rates, number of repeat embolizations, survival times, and causes of death.

Results: BAE was performed on 38 occasions in 20 patients. The mean age of patients at first BAE was 15 years (age range, 7-19 years). The majority (n = 34 [89%]) of BAEs were performed by using polyvinyl alcohol. The immediate success rate after BAE (ie, no recurrent bleeding within 24 hours) was 95% (36 of 38 BAEs). Eleven (55%) patients required more than one BAE, and the median time between first and second embolizations was 4 months (range, 5 days to 61 months). Three patients died as a consequence of severe hemoptysis during induction of anesthesia with intermittent positive pressure ventilation in preparation for BAE. The median survival duration after the first BAE (Kaplan-Meier estimate) was 84 months (average follow-up, 61 months; range, 5 days to 169 months).

Conclusion: BAE had a high success rate for short-term control of bleeding; however, more than half the patients required repeat embolization during the long-term follow-up.

MeSH terms

  • Adolescent
  • Adult
  • Bronchial Arteries*
  • Child
  • Cystic Fibrosis / complications*
  • Embolization, Therapeutic*
  • Female
  • Follow-Up Studies
  • Hemoptysis / mortality
  • Hemoptysis / therapy*
  • Humans
  • Male
  • Polyvinyl Alcohol
  • Retrospective Studies
  • Treatment Outcome


  • Polyvinyl Alcohol