Software and methods for oligonucleotide and cDNA array data analysis

Genome Biol. 2002;3(6):SOFTWARE0001. doi: 10.1186/gb-2002-3-6-software0001. Epub 2002 May 23.


Two HTML-based programs were developed to analyze and filter gene-expression data: 'Bullfrog' for Affymetrix oligonucleotide arrays and 'Spot' for custom cDNA arrays. The programs provide intuitive data-filtering tools through an easy-to-use interface. A background subtraction and normalization program for cDNA arrays was also built that provides an informative summary report with data-quality assessments. These programs are freeware to aid in the analysis of gene-expression results and facilitate the search for genes responsible for interesting biological processes and phenotypes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computational Biology / instrumentation
  • Computational Biology / methods
  • DNA, Complementary / analysis*
  • DNA, Complementary / genetics
  • Database Management Systems / trends
  • Databases, Genetic / trends
  • Gene Expression Profiling / instrumentation
  • Gene Expression Profiling / methods
  • Oligonucleotide Array Sequence Analysis / instrumentation*
  • Oligonucleotide Array Sequence Analysis / methods*
  • Oligonucleotides / genetics*
  • Software* / trends


  • DNA, Complementary
  • Oligonucleotides