Abstract
The recognition of microbial pathogens based on their molecular patterns is essential for host defense. Recently, Toll-like receptors have been shown not only to recognize viruses as well as bacteria and fungi, but also to trigger an efficient immune response. A recent publication proposed that the retrovirus mouse mammary tumor virus exploits the pattern-recognition receptor Toll-like receptor 4 to achieve more efficient infection.
MeSH terms
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Animals
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B-Lymphocytes / immunology*
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B-Lymphocytes / virology
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Drosophila Proteins*
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Mammary Tumor Virus, Mouse / immunology*
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Membrane Glycoproteins / genetics
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Membrane Glycoproteins / immunology*
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Mice
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Receptors, Cell Surface / genetics
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Receptors, Cell Surface / immunology*
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Toll-Like Receptor 4
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Toll-Like Receptors
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Viral Envelope Proteins / immunology
Substances
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Drosophila Proteins
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Membrane Glycoproteins
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Receptors, Cell Surface
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Toll-Like Receptor 4
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Toll-Like Receptors
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Viral Envelope Proteins