A Pearson-type goodness-of-fit test for stationary and time-continuous Markov regression models

Stat Med. 2002 Jul 15;21(13):1899-911. doi: 10.1002/sim.1152.

Abstract

Markov regression models describe the way in which a categorical response variable changes over time for subjects with different explanatory variables. Frequently it is difficult to measure the response variable on equally spaced discrete time intervals. Here we propose a Pearson-type goodness-of-fit test for stationary Markov regression models fitted to panel data. A parametric bootstrap algorithm is used to study the distribution of the test statistic. The proposed technique is applied to examine the fit of a Markov regression model used to identify markers for disease progression in psoriatic arthritis.

MeSH terms

  • Arthritis, Psoriatic / drug therapy
  • Arthritis, Psoriatic / pathology
  • Blood Sedimentation / drug effects
  • Disease Progression
  • Humans
  • Longitudinal Studies
  • Markov Chains*
  • Regression Analysis*