Corticobasal degeneration syndrome with basal ganglia calcification: Fahr's disease as a corticobasal look-alike?

Mov Disord. 2002 May;17(3):563-7. doi: 10.1002/mds.10122.


A 57-year-old man with a 5-year history of progressive left-sided rigidity and apraxia had extensive bilateral calcification of basal ganglia, centrum semiovale, dentate nuclei, and cerebellar white matter on brain imaging. The case is an example of radiological Fahr's disease accompanying a clinical syndrome of corticobasal degeneration. Possible pathogenetic and nosological implications of this association are discussed.

Publication types

  • Case Reports

MeSH terms

  • Basal Ganglia Diseases / complications*
  • Basal Ganglia Diseases / diagnostic imaging
  • Basal Ganglia Diseases / pathology
  • Calcinosis / complications*
  • Calcinosis / diagnostic imaging
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Neurodegenerative Diseases / complications*
  • Neurodegenerative Diseases / diagnostic imaging
  • Neurodegenerative Diseases / pathology
  • Syndrome
  • Tomography, X-Ray Computed