Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
, 1 (2), 153-61

Metabonomics: A Platform for Studying Drug Toxicity and Gene Function

Affiliations
Review

Metabonomics: A Platform for Studying Drug Toxicity and Gene Function

Jeremy K Nicholson et al. Nat Rev Drug Discov.

Abstract

The later that a molecule or molecular class is lost from the drug development pipeline, the higher the financial cost. Minimizing attrition is therefore one of the most important aims of a pharmaceutical discovery programme. Novel technologies that increase the probability of making the right choice early save resources, and promote safety, efficacy and profitability. Metabonomics is a systems approach for studying in vivo metabolic profiles, which promises to provide information on drug toxicity, disease processes and gene function at several stages in the discovery-and-development process.

Similar articles

See all similar articles

Cited by 300 PubMed Central articles

See all "Cited by" articles

Publication types

LinkOut - more resources

Feedback