Adhesion of viridans group streptococci to sialic acid-, galactose- and N-acetylgalactosamine-containing receptors

Oral Microbiol Immunol. 2002 Aug;17(4):257-62. doi: 10.1034/j.1399-302x.2002.170409.x.

Abstract

The binding of 10 viridans group streptococci to sialic acid-, galactose (Gal)- and N-acetylgalactosamine (GalNAc)-containing receptors was defined by analysis of the interactions between these bacteria and structurally defined glycoconjugates, host cells and other streptococci. All interactions with sialic acid-containing receptors were Ca(2+)-independent as they were not affected by ethyleneglycoltetraacetic acid (EGTA), whereas all interactions with Gal- and GalNAc-containing receptors were Ca(2+)-dependent. Recognition of sialic acid-, Gal- and GalNAc-containing receptors varied widely among the strains examined, in a manner consistent with the association of each of the three lectin-like activities with a different bacterial cell surface component.

MeSH terms

  • Acetylgalactosamine / metabolism
  • Bacterial Adhesion / physiology*
  • Biofilms
  • Calcium / metabolism
  • Galactose / metabolism
  • Glycoconjugates / metabolism*
  • N-Acetylneuraminic Acid / metabolism
  • Receptors, Cell Surface / metabolism*
  • Receptors, Immunologic / metabolism*
  • Viridans Streptococci / physiology*

Substances

  • Glycoconjugates
  • Receptors, Cell Surface
  • Receptors, Immunologic
  • bacterial adhesin receptor
  • N-Acetylneuraminic Acid
  • Acetylgalactosamine
  • Calcium
  • Galactose