Catalytic direct 1,4-conjugate addition of aldehydes to vinylketones on secondary-amines immobilised in FSM-16 silica

Chem Commun (Camb). 2002 May 21:(10):1068-9. doi: 10.1039/b202488h.

Authors

Ken-ichi Shimizu¹, Hiromasa Suzuki, Eidai Hayashi, Tatsuya Kodama, Yoshimi Tsuchiya, Hisahiro Hagiwara, Yoshie Kitayama

Affiliation

¹ Graduate School of Science and Technology, Niigata University, Ikarashi-2, Niigata 950-2181, Japan.

PMID: 12122668
DOI: 10.1039/b202488h

Abstract

Direct 1,4-conjugate addition of naked aldehydes to vinylketones is catalysed effectively by N-methyl-3-aminopropylated FSM-16 mesoporous silica, which can be regarded as a novel heterogeneous catalysis for a practical C-C bond formation reaction.