First in vitro norlignan formation with Asparagus officinalis enzyme preparation

Shiro Suzuki; Tomoyuki Nakatsubo; Toshiaki Umezawa; Mikio Shimada

doi:10.1039/b200217e

First in vitro norlignan formation with Asparagus officinalis enzyme preparation

Chem Commun (Camb). 2002 May 21:(10):1088-9. doi: 10.1039/b200217e.

Authors

Shiro Suzuki¹, Tomoyuki Nakatsubo, Toshiaki Umezawa, Mikio Shimada

Affiliation

¹ Wood Research Institute, Kyoto University, Uji, Kyoto 611-0011, Japan.

PMID: 12122678
DOI: 10.1039/b200217e

Abstract

We report for the first time that an enzyme preparation from fungal-elicited Asparagus officinalis cultured cells catalyses the formation of a norlignan, (Z)-hinokiresinol, from two non-identical phenylpropanoid monomers, 4-coumaryl alcohol and 4-coumaroyl CoA, and from a dimer, 4-coumaryl 4-coumarate, without any additional cofactors.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acyl Coenzyme A / metabolism*
Asparagus Plant / cytology
Asparagus Plant / enzymology
Asparagus Plant / metabolism*
Cells, Cultured
Lignans / biosynthesis*
Mass Spectrometry

Substances

Acyl Coenzyme A
Lignans
4-coumaroyl-coenzyme A