Scleroderma and Smads: dysfunctional Smad family dynamics culminating in fibrosis

Arthritis Rheum. 2002 Jul;46(7):1703-13. doi: 10.1002/art.10413.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • DNA-Binding Proteins / physiology*
  • Fibrosis / pathology*
  • Humans
  • Scleroderma, Systemic / metabolism
  • Scleroderma, Systemic / pathology*
  • Signal Transduction / physiology
  • Smad Proteins
  • Trans-Activators / physiology*
  • Transforming Growth Factor beta / physiology*

Substances

  • DNA-Binding Proteins
  • Smad Proteins
  • Trans-Activators
  • Transforming Growth Factor beta