Objective: To evaluate the effect of endovascular embolization with alpha-NBCA on cerebral arteriovenous malformation with NBCA and emphasize the mainpoint of the embolizing technique.
Methods: 469 patients with cerebral arteriovenous malformation underwent endovascular embolization with alpha-NBCA by using microcatheter under digital subtraction angiography.
Results: 469 patients were treated successfully, 467 cases recovered clinically, 2 patients died. 469 patients underwent embolization therapy 1 108 times, ranging 1 to 8 times with an average of 2.3 times. 100% embolization was achieved in 155 cases, 90% approximately 100% in 93, 80% approximately 90% in 105, 70% approximately 80% in 78, 60% approximately 70% in 27, below 60% in 11. Nineteen cases received gamma-knife (or X-knife) therapy alone. 117 cases received gamma-knife (or X-knife) therapy after embolization, 32 cases received operations. Six cases suffered from different complications: 1 case with cerebral infarction recovered after urokinase injection, 4 cases suffered from intracranial hemorrhage, and 1 suffered from catheter resorting in nidus.
Conclusion: Endovascular embolization is a safe, reliable and effective treatment for cerebral arteriovenous malformation.