Successive pregnancies with delivery of two healthy infants in a couple who was discordant for human immunodeficiency virus infection

Fertil Steril. 2002 Aug;78(2):421-3. doi: 10.1016/s0015-0282(02)03213-2.


Objective: To describe two successive pregnancies resulting in two healthy infants in an HIV-discordant couple who underwent IVF-ICSI.

Design: Case report.

Setting: University-based infertility clinic.

Patient(s): A couple seeking fertility treatment in which the male partner was seropositive for HIV-1.

Intervention(s): Controlled ovarian hyperstimulation and IVF-ET with ICSI.

Main outcome measure(s): Pregnancy outcome and HIV-1 seroconversion.

Result(s): The couple delivered two healthy infants on successive pregnancies with use of IVF-ET with ICSI.

Conclusion(s): For HIV-discordant couples in which the male partner is seropositive for HIV-1, IVF with ICSI is a viable option.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Embryo Transfer
  • Female
  • HIV Seronegativity*
  • HIV Seropositivity*
  • HIV-1*
  • Humans
  • Male
  • Middle Aged
  • Pregnancy
  • Pregnancy Outcome*
  • Sperm Injections, Intracytoplasmic*