Genetic detection and isolation of crimean-congo hemorrhagic fever virus, Kosovo, Yugoslavia

Emerg Infect Dis. 2002 Aug;8(8):852-4. doi: 10.3201/eid0808.010448.

Abstract

Crimean-Congo hemorrhagic fever virus (C-CHFV) strains were isolated from a fatal case and the attending physician in Kosovo, Yugoslavia. Early, rapid diagnosis of the disease was achieved by reverse transcription-polymerase chain reaction. The physician was successfully treated with oral ribavirin. These cases yielded the first genetically studied C-CHFV human isolates in the Balkans.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antiviral Agents / therapeutic use
  • Female
  • Hemorrhagic Fever Virus, Crimean-Congo / genetics*
  • Hemorrhagic Fever Virus, Crimean-Congo / isolation & purification*
  • Hemorrhagic Fever, Crimean / drug therapy*
  • Hemorrhagic Fever, Crimean / virology*
  • Humans
  • Male
  • Phylogeny
  • Polymerase Chain Reaction
  • Precipitin Tests
  • RNA, Viral / genetics
  • Ribavirin / therapeutic use
  • Yugoslavia

Substances

  • Antiviral Agents
  • RNA, Viral
  • Ribavirin