Correlates of procedural complications and a simple integer risk score for percutaneous coronary intervention

J Am Coll Cardiol. 2002 Aug 7;40(3):387-93. doi: 10.1016/s0735-1097(02)01980-0.


Objectives: Our goals were to identify clinical and angiographic risk factors associated with major cardiovascular complications of percutaneous coronary intervention (PCI) (in-hospital death, Q-wave myocardial infarction, urgent or emergent coronary artery bypass surgery and stroke) and to construct a simple score for risk stratification.

Background: Both clinical and angiographic features influence risk of PCIs.

Methods: Percutaneous coronary interventions performed between January 1, 1996, and December 31, 1999, were analyzed. Logistic regression and bootstrap methods were used to create an integer risk score for estimating the risk of procedural complications using baseline, angiographic and procedural characteristics. The risk score was tested in a validation-set consisting of all procedures performed in the year 2000.

Results: Among 5,463 procedures, 5 clinical and 3 angiographic variables were significantly correlated with procedural complications: cardiogenic shock, left main coronary artery disease, severe renal disease, urgent or emergent procedure, congestive heart failure class III or higher, thrombus, multivessel disease and older age. In the validation-set, the model fitted the data adequately; the average receiver operating characteristic curve area was 0.782 (standard deviation, 0.018).

Conclusions: Eight variables were combined into a convenient bedside risk scoring system that estimates the risk of complications after PCIs.

Publication types

  • Comparative Study
  • Validation Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Angioplasty, Balloon, Coronary / adverse effects*
  • Angioplasty, Balloon, Coronary / mortality
  • Coronary Artery Bypass
  • Female
  • Follow-Up Studies
  • Hospital Mortality
  • Humans
  • Logistic Models
  • Male
  • Middle Aged
  • Minnesota / epidemiology
  • Multivariate Analysis
  • Myocardial Ischemia / diagnostic imaging
  • Myocardial Ischemia / mortality
  • Myocardial Ischemia / therapy
  • Postoperative Complications / diagnostic imaging
  • Postoperative Complications / etiology*
  • Postoperative Complications / mortality
  • Prevalence
  • ROC Curve
  • Radiography
  • Risk Factors
  • Statistics as Topic
  • Treatment Failure