Struma ovarii associated with pseudo-Meigs' syndrome and elevated serum CA 125

Gynecol Oncol. 2002 Aug;86(2):231-4. doi: 10.1006/gyno.2002.6741.


Background: Struma ovarii, presenting as pseudo-Meigs' syndrome with an elevated CA 125 level, is a rare condition.

Case: A 65-year-old patient presented with ascites, hydrothorax, right ovarian mass, and elevated CA 125 level. These findings were suspicious for an ovarian malignancy. The mass was removed and revealed struma ovarii, a specialized ovarian teratoma composed predominantly of mature thyroid tissue. In the setting of ascites and hydrothorax, the condition is known as pseudo-Meigs' syndrome. This is the second reported case in the English language literature of pseudo-Meigs' syndrome with an elevated CA 125 level resulting from struma ovarii.

Conclusion: Struma ovarii is a rare cause of ascites, hydrothorax, and an elevated CA 125 level.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Ascites / etiology*
  • Ascites / immunology
  • CA-125 Antigen / blood*
  • Female
  • Humans
  • Hydrothorax / etiology*
  • Hydrothorax / immunology
  • Meigs Syndrome / etiology
  • Struma Ovarii / complications*
  • Struma Ovarii / immunology


  • CA-125 Antigen