Haemolysis associated with diazoxide, used for the control of hypertension

Postgrad Med J. 1975 Jun;51(596):402-4. doi: 10.1136/pgmj.51.596.402.


Diazoxide, an agent used occasionally in the control of hypertension, has been associated with three haemolytic episodes in one patient. It is suggested that the mode of action is similar to that of diaminodiphenyl sulphone (dapsone) in acting as an oxidant stress to the ageing erythrocyte.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Diazoxide / adverse effects
  • Diazoxide / therapeutic use*
  • Hemolysis / drug effects*
  • Humans
  • Hypertension / drug therapy*
  • Male


  • Diazoxide