Synthesis and antimicrobial activity of some pyridinyliminothiazoline derivatives

G Turan-Zitouni; D M Sivaci; Z A Kaplancikli; A Ozdemir

doi:10.1016/s0014-827x(02)01250-8

Synthesis and antimicrobial activity of some pyridinyliminothiazoline derivatives

Farmaco. 2002 Jul;57(7):569-72. doi: 10.1016/s0014-827x(02)01250-8.

Authors

G Turan-Zitouni¹, D M Sivaci, Z A Kaplancikli, A Ozdemir

Affiliation

¹ Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Anadolu, Eskişehir, Turkey. gzitouni@anadolu.edu.tr

PMID: 12164216
DOI: 10.1016/s0014-827x(02)01250-8

Abstract

The synthesis of some pyridinyliminothiazoline derivatives starting from N-pyridine-N'-phenyl thiourea and alpha-halogenoacetophenones is described. The chemical structures of the compounds were elucidated. The prepared compounds were tested for antimicrobial activity.

MeSH terms

Anti-Bacterial Agents
Anti-Infective Agents / chemical synthesis*
Anti-Infective Agents / chemistry
Anti-Infective Agents / pharmacology
Candida albicans / drug effects*
Gram-Negative Bacteria / drug effects
Gram-Positive Bacteria / drug effects
Magnetic Resonance Spectroscopy
Microbial Sensitivity Tests
Molecular Structure
Thiazoles / chemical synthesis*
Thiazoles / chemistry
Thiazoles / pharmacology

Substances

Anti-Bacterial Agents
Anti-Infective Agents
Thiazoles