Analgesic and anti-inflammatory effects of the aqueous extract of leaves of Persea americana mill (lauraceae)

Fitoterapia. 2002 Aug;73(5):375-80. doi: 10.1016/s0367-326x(02)00118-1.


The aqueous extract of Persea americana leaves produced a dose-dependent inhibition of both phases of formalin pain test in mice, a reduction in mouse writhing induced by acetic acid and an elevation of pain threshold in the hot plate test in mice. The extract also produced a dose-dependent inhibition of carrageenan-induced rat paw oedema. The results obtained indicate that the extract possesses analgesic and anti-inflammatory effects.

MeSH terms

  • Analgesics / pharmacology*
  • Analgesics, Non-Narcotic / pharmacology*
  • Animals
  • Female
  • Lauraceae / chemistry*
  • Male
  • Mice
  • Nigeria
  • Plant Extracts / pharmacology*
  • Plant Leaves / chemistry*
  • Plants, Medicinal / chemistry
  • Rats
  • Rats, Wistar


  • Analgesics
  • Analgesics, Non-Narcotic
  • Plant Extracts