A novel phenanthrenolide and C-benzyl dihydrochalcones from Uvaria puguensis

Nat Prod Lett. 2002 Aug;16(4):267-72. doi: 10.1080/10575630290020604.

Abstract

Two new natural products, the phenanthrenoid puguenolide (6-hydroxy-3-methoxy-4-oxapyren-5-one) and isoangoletin were isolated from the stem bark of the newly described Uvaria species, U. puguensis D.M. Johnson, together with the sesquiterpene guaiol and the usual C-benzyldihydrochalcones previously found in the genus Uvaria, viz. uvaretin, diuvaretin, chamuvaritin and a mixture of triuvaretin and isotriuvaretin. Structural elucidation was achieved through a combination of spectroscopic methods.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chalcone / analogs & derivatives
  • Chalcone / chemistry
  • Chalcone / isolation & purification*
  • Heterocyclic Compounds, 4 or More Rings / chemistry
  • Heterocyclic Compounds, 4 or More Rings / isolation & purification*
  • Medicine, African Traditional*
  • Molecular Conformation
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Phenanthrenes / chemistry
  • Phenanthrenes / isolation & purification*
  • Plant Bark / chemistry
  • Plant Stems / chemistry
  • Pyrones / chemistry
  • Pyrones / isolation & purification*
  • Spectroscopy, Fourier Transform Infrared
  • Tanzania
  • Uvaria / chemistry*

Substances

  • 6-hydroxy-3-methoxy-4-oxapyren-5-one
  • Heterocyclic Compounds, 4 or More Rings
  • Phenanthrenes
  • Pyrones
  • isoangoletin
  • Chalcone