Abstract
Although most patients with cancer pain can attain a favorable balance between analgesia and side effects with a conventional approach to opioid therapy, a substantial minority cannot. For these patients, an important subgroup of whom have neuropathic pain, alternative therapeutic strategies are needed. With a detailed assessment, clinicians should be able to choose among the large and diverse group of options available and implement an approach, or combination of approaches, that have a high probability of improving analgesic outcomes.
MeSH terms
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Analgesics, Opioid / adverse effects
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Analgesics, Opioid / therapeutic use*
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Anesthetics, Local / therapeutic use
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Anti-Inflammatory Agents / therapeutic use
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Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
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Anticonvulsants / therapeutic use
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Dose-Response Relationship, Drug
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Drug Administration Schedule
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Drug Therapy, Combination
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Humans
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Neoplasms / complications*
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Pain / diagnosis
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Pain / drug therapy*
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Pain / etiology*
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Pain Measurement
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Palliative Care / methods
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Patient Care Planning
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Patient Selection
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Psychotropic Drugs / therapeutic use
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Receptors, N-Methyl-D-Aspartate / antagonists & inhibitors
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Steroids
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Treatment Outcome
Substances
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Analgesics, Opioid
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Anesthetics, Local
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Anti-Inflammatory Agents
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Anti-Inflammatory Agents, Non-Steroidal
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Anticonvulsants
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Psychotropic Drugs
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Receptors, N-Methyl-D-Aspartate
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Steroids