Secular trend of hospital-acquired candidemia among intensive care unit patients in the United States during 1989-1999

Clin Infect Dis. 2002 Sep 1;35(5):627-30. doi: 10.1086/342300. Epub 2002 Aug 2.


We describe the annual incidence of primary bloodstream infection (BSI) associated with Candida albicans and common non-albicans species of Candida among patients in intensive care units that participated in the National Nosocomial Infections Surveillance system from 1 January 1989 through 31 December 1999. During the study period, there was a significant decrease in the incidence of C. albicans BSI (P<.001) and a significant increase in the incidence of Candida glabrata BSI (P=.05).

MeSH terms

  • Adult
  • Candida / isolation & purification*
  • Candidiasis / epidemiology*
  • Candidiasis / microbiology
  • Cross Infection / epidemiology*
  • Cross Infection / microbiology
  • Female
  • Humans
  • Intensive Care Units
  • Male
  • Middle Aged
  • United States / epidemiology