Central giant cell granuloma

Int J Pediatr Otorhinolaryngol. 2002 Sep 2;65(2):143-6. doi: 10.1016/s0165-5876(02)00118-0.


The central giant cell granuloma (CGCG) is an uncommon benign bony lesion that accounts for less than 7% of all benign lesions of the jaws in tooth-bearing areas. Its etiology is unknown and its biological behavior is poorly understood. This condition is a slow-growing, asymptomatic lesion that usually affects children and young adults, predominantly females. The following report illustrates the differential diagnosis, surgery, final diagnosis and pathology of a fast-growing CGCG in a 4-year-old girl.

Publication types

  • Case Reports

MeSH terms

  • Biopsy, Needle
  • Child, Preschool
  • Curettage / methods
  • Female
  • Follow-Up Studies
  • Granuloma, Giant Cell / pathology*
  • Granuloma, Giant Cell / surgery
  • Humans
  • Immunohistochemistry
  • Mandibular Diseases / pathology*
  • Mandibular Diseases / surgery
  • Tomography, X-Ray Computed
  • Treatment Outcome