Properties of polyethylene glycol 660 12-hydroxy stearate at a triglyceride/water interface

Int J Pharm. 2002 Aug 21;242(1-2):167-70. doi: 10.1016/s0378-5173(02)00144-8.

Abstract

This study proposed a method to understand the surfactant role in the first step of the formulation of a novel generation of lipidic nanocapsules. A dynamic rheological protocol was applied using a pendant drop tensiometer in order to determine the interfacial properties of the initial mixture implied in the first formulation step. The response, in terms of interfacial elasticities, described how this mixture led to monodisperse nanometer size range structures after a physico-chemical constraint.

MeSH terms

  • Capsules
  • Chemical Phenomena
  • Chemistry, Physical
  • Emulsions
  • Polyethylene Glycols / chemistry
  • Rheology
  • Stearates / chemistry
  • Surface Tension
  • Surface-Active Agents
  • Triglycerides / chemistry*
  • Water

Substances

  • Capsules
  • Emulsions
  • Stearates
  • Surface-Active Agents
  • Triglycerides
  • polyethylene glycol 660 12-hydroxy stearate
  • Water
  • Polyethylene Glycols