Innate immunity in plants and animals: emerging parallels between the recognition of general elicitors and pathogen-associated molecular patterns

Curr Opin Plant Biol. 2002 Aug;5(4):318-24. doi: 10.1016/s1369-5266(02)00265-0.


Recent findings have highlighted remarkable similarities in the innate pathogen defense systems of plants, animals and insects. Pathogen-associated molecular patterns (PAMP) that are similar to those activating innate immune responses in animals have been shown to mediate the activation of plant defense. Moreover, recognition complexes that are structurally related to animal PAMP receptors are now being discovered in plants, suggesting a common evolutionary origin of pathogen defense systems in higher eukaryotes.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Evolution, Molecular
  • Immunity, Innate / genetics
  • Immunity, Innate / physiology*
  • Plants / genetics*
  • Plants / microbiology
  • Plants / parasitology
  • Proteins / genetics
  • Proteins / metabolism


  • Proteins
  • leucine-rich repeat proteins