[New biological properties of p-aminobenzoic acid]

Izv Akad Nauk Ser Biol. Jul-Aug 2002;(4):477-81.
[Article in Russian]

Abstract

p-Aminobenzoic acid (PABA) is a cyclic amino acid, belongs to the vitamin B group, and is used as a protective drug against solar insolation and in diagnostic tests for the state of the gastrointestinal tract in medicine. We were the first to establish that PABA is an inducer of endogenous interferon and immunomodulator and displays a virucidal, synergistic antiviral effect when combined with chemical drugs and the properties of a direct anticoagulant. Based on these properties, we elaborated a new medicinal drug "Actipol" which was introduced in clinical practice.

Publication types

  • English Abstract
  • Review

MeSH terms

  • 4-Aminobenzoic Acid / pharmacology*
  • Animals
  • Anti-Bacterial Agents / pharmacology
  • Anticoagulants / pharmacology
  • Antioxidants / pharmacology
  • Antiviral Agents / pharmacology*
  • Drug Synergism
  • Eye Diseases / drug therapy
  • Eye Diseases / virology
  • Eye Infections, Viral / drug therapy
  • Humans
  • Interferons / metabolism

Substances

  • Anti-Bacterial Agents
  • Anticoagulants
  • Antioxidants
  • Antiviral Agents
  • Interferons
  • 4-Aminobenzoic Acid