Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2002 Aug 22;4(17):2965-7.
doi: 10.1021/ol026378e.

Short Total Synthesis of 8,10-di-O-methylbergenin

Affiliations

Short Total Synthesis of 8,10-di-O-methylbergenin

Holger Herzner et al. Org Lett. .

Abstract

[reaction: see text] A short, high-yielding synthesis of the C-glucoside 8,10-di-O-methylbergenin is reported. Key elements of the synthesis are a stereoselective installation of a beta-C-aryl linkage, a palladium(0)-catalyzed aryl carbonylation, and a regioselective lactonization reaction. This pathway should allow access to a host of bergenin analogues.

Similar articles

See all similar articles

Publication types

MeSH terms

LinkOut - more resources

Feedback