Hydrogen peroxide signalling

Curr Opin Plant Biol. 2002 Oct;5(5):388-95. doi: 10.1016/s1369-5266(02)00282-0.


Recent biochemical and genetic studies confirm that hydrogen peroxide is a signalling molecule in plants that mediates responses to abiotic and biotic stresses. Signalling roles for hydrogen peroxide during abscisic-acid-mediated stomatal closure, auxin-regulated root gravitropism and tolerance of oxygen deprivation are now evident. The synthesis and action of hydrogen peroxide appear to be linked to those of nitric oxide. Downstream signalling events that are modulated by hydrogen peroxide include calcium mobilisation, protein phosphorylation and gene expression. Calcium and Rop signalling contribute to the maintenance of hydrogen peroxide homeostasis.

Publication types

  • Review

MeSH terms

  • Abscisic Acid / pharmacology
  • Apoptosis / drug effects
  • Gene Expression Regulation, Plant / drug effects
  • Gravitropism / drug effects
  • Hydrogen Peroxide / metabolism*
  • Hydrogen Peroxide / pharmacology
  • Indoleacetic Acids / pharmacology
  • Plant Roots / drug effects
  • Plants / drug effects
  • Plants / genetics
  • Plants / metabolism*
  • Signal Transduction* / drug effects


  • Indoleacetic Acids
  • Abscisic Acid
  • Hydrogen Peroxide