Physical activity, dietary intake, and the insulin resistance syndrome in nondiabetic adults with mental retardation

Am J Ment Retard. 2002 Sep;107(5):361-75. doi: 10.1352/0895-8017(2002)107<0361:PADIAT>2.0.CO;2.

Abstract

The association between physical activity, dietary behaviors, and elevated cardiovascular disease risk factor components of the insulin resistance syndrome in adults with mental retardation was identified. Established clinical cutoff points were used to identify 145 participants with mild mental retardation and hyperinsulinemia, borderline high triglycerides, low high-density lipoprotein cholesterol, hypertension, and abdominal obesity. Odds ratios were calculated from logistic regression analysis. Those who participated in more frequent bouts of physical activity or who consumed lower dietary fat intakes were approximately one third as likely to have hyperinsulinemia and abdominal obesity compared to those who participated in less frequent physical activity or who consumed higher fat intakes, suggesting that these behaviors are protective against elevated components of the insulin resistance syndrome.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Body Constitution / physiology
  • Cholesterol, HDL / blood
  • Cross-Sectional Studies
  • Diabetes Mellitus, Type 2 / diagnosis
  • Diabetes Mellitus, Type 2 / physiopathology
  • Diabetes Mellitus, Type 2 / psychology
  • Exercise / physiology*
  • Feeding Behavior / physiology*
  • Feeding Behavior / psychology
  • Female
  • Humans
  • Hypertension / diagnosis
  • Hypertension / physiopathology
  • Hypertension / psychology
  • Insulin / blood
  • Insulin Resistance / physiology*
  • Intellectual Disability / physiopathology*
  • Intellectual Disability / psychology
  • Male
  • Metabolic Syndrome / diagnosis*
  • Metabolic Syndrome / physiopathology
  • Metabolic Syndrome / psychology
  • Middle Aged
  • Obesity / diagnosis
  • Obesity / physiopathology
  • Obesity / psychology
  • Risk Factors
  • Triglycerides / blood

Substances

  • Cholesterol, HDL
  • Insulin
  • Triglycerides