Minor steroidal alkaloids from the marine sponge Corticium sp
- PMID: 12193035
- DOI: 10.1021/np020027r
Minor steroidal alkaloids from the marine sponge Corticium sp
Abstract
Four new steroidal alkaloids, plakinamine G (1), plakinamine H (2), 4alpha-hydroxydemethylplakinamine B (3), and tetrahydroplakinamine A (4), along with three known compounds, were isolated from the marine sponge Corticium sp. The structures of these metabolites were elucidated largely by 1D and 2D NMR methods and accurate mass measurements (HR-EIMS). Compounds 1, 2, and 4 show significant in vitro cytotoxicity.
Similar articles
-
New cytotoxic steroidal alkaloids from the Philippine sponge Corticium niger.J Nat Prod. 2003 Dec;66(12):1536-9. doi: 10.1021/np0302706. J Nat Prod. 2003. PMID: 14695791
-
Plakinamine M, a steroidal alkaloid from the marine sponge Corticium sp.J Nat Prod. 2013 Nov 22;76(11):2150-2. doi: 10.1021/np400649e. Epub 2013 Nov 6. J Nat Prod. 2013. PMID: 24195491 Free PMC article.
-
New steroidal alkaloids from an undescribed sponge of the genus Corticium.J Nat Prod. 2001 Nov;64(11):1474-6. doi: 10.1021/np0101649. J Nat Prod. 2001. PMID: 11720539
-
Novel antitumor agents: marine sponge alkaloids, their synthetic analogs and derivatives.Mini Rev Med Chem. 2005 Mar;5(3):319-36. doi: 10.2174/1389557053175362. Mini Rev Med Chem. 2005. PMID: 15777266 Review.
-
Important classes of bioactive alkaloids from marine ascidians: structures, isolation and bioactivity.Curr Top Med Chem. 2014;14(2):207-23. doi: 10.2174/1568026613666131213155813. Curr Top Med Chem. 2014. PMID: 24359200 Review.
Cited by
-
Small Molecules of Marine Origin as Potential Anti-Glioma Agents.Molecules. 2021 May 5;26(9):2707. doi: 10.3390/molecules26092707. Molecules. 2021. PMID: 34063013 Free PMC article. Review.
-
The Role of Nutrition and Forest-Bathing in the Physical Rehabilitation of Physically Inactive Patients: From the Molecular Aspects to New Nature-Inspired Techniques.Int J Environ Res Public Health. 2022 Dec 31;20(1):793. doi: 10.3390/ijerph20010793. Int J Environ Res Public Health. 2022. PMID: 36613115 Free PMC article. Review.
-
Halogenated cyclic peptides isolated from the sponge Corticium sp.J Nat Prod. 2007 May;70(5):741-6. doi: 10.1021/np060489v. Epub 2007 Mar 29. J Nat Prod. 2007. PMID: 17391049 Free PMC article.
-
Recent N-atom containing compounds from indo-pacific invertebrates.Mar Drugs. 2010 Nov 10;8(11):2810-36. doi: 10.3390/md8112810. Mar Drugs. 2010. PMID: 21139846 Free PMC article. Review.
-
Exploring the Relationship between G-Quadruplex Nucleic Acids and Plants: From Plant G-Quadruplex Function to Phytochemical G4 Ligands with Pharmaceutic Potential.Pharmaceutics. 2022 Nov 4;14(11):2377. doi: 10.3390/pharmaceutics14112377. Pharmaceutics. 2022. PMID: 36365194 Free PMC article. Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
