[Familial transient red cell aplasia from parvovirus B-19 infection]

Pediatr Med Chir. 2002 Jul-Aug;24(4):306-7.
[Article in Italian]


In our Paediatric Clinic we observed a case of transient aplastic crisis caused by Parvovirus B19 in a child and his mother, both affected by spherocytic haemolytic anemia. Anti-Parvovirus IgM antibody titre and viral search by PCR were positive. Anemia was treated with transfusion of concentrated red blood cells. In case of a family onset of hyperacute anemia it is necessary to consider a bone marrow aplastic crisis of the red series, induced by Parvovirus B19, especially if there is notice of an ongoing outbreak of erythema infectiosum.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Antibodies, Viral / immunology
  • Female
  • Humans
  • Immunoglobulin M / immunology
  • Infant, Newborn
  • Male
  • Parvoviridae Infections / drug therapy
  • Parvoviridae Infections / immunology
  • Parvoviridae Infections / virology*
  • Parvovirus B19, Human / immunology
  • Parvovirus B19, Human / isolation & purification*
  • Polymerase Chain Reaction
  • Red-Cell Aplasia, Pure / genetics*
  • Red-Cell Aplasia, Pure / virology*
  • Spherocytosis, Hereditary / genetics*


  • Antibodies, Viral
  • Immunoglobulin M