Candidemia in French hospitals: incidence rates and characteristics

Clin Microbiol Infect. 2002 Jul;8(7):405-12. doi: 10.1046/j.1469-0691.2002.00446.x.


Objective: To determine the incidence of candidemia in French hospitals.

Materials and methods: A representative sample of 25 French hospitals [nine teaching hospitals (TH), ten general hospitals (GH) and six cancer referral centers (CRC)] was randomly selected. The incidence rates of candidemia per number of admissions and per patient-days of hospitalization were determined and extrapolated to the national level.

Results: From January 1, 1995 to December 31, 1995, the overall incidence rate per 1000 admissions was 0.29, ranging from 0.71/1000 in CRC, to 0.17/1000 in GH. The overall incidence for 1000 patient-days was 0.035 and the highest incidence was also observed in CRC (0.116/1000), followed by TH (0.052/1000). Candida albicans (53%) was the most common species isolated, a central venous catheter (26%) was the most common portal of entry and 50% of the candidaemic patients had a neoplasm.

Conclusion: This study should enable us to optimize surveillance, prevention and treatment of these potentially life-threatening infections.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Candida / classification
  • Candida / isolation & purification*
  • Candidiasis / blood
  • Candidiasis / epidemiology*
  • Candidiasis / microbiology
  • Female
  • France / epidemiology
  • Fungemia / blood
  • Fungemia / epidemiology*
  • Fungemia / microbiology
  • Hospitals
  • Humans
  • Incidence
  • Male
  • Risk Factors