Unilateral retinal vasculitis, branch retinal artery occlusion and subsequent retinal neovascularization in Crohn's disease

Int Ophthalmol. 2001;24(2):89-92. doi: 10.1023/a:1016351800466.


Purpose: To report on a case of Crohn's disease and unilateral retinal vasculitis, branch retinal artery occlusion and subsequent retinal neovascularization.

Methods: We examined a 38-year-old woman with severe left visual loss and biopsy-proven Crohn's disease diagnosed four years prior to the ocular involvement. A Heidelberg scanning laser ophthalmoscope was used for fundus fluorescein angiography and indocyanine green angiography. Retinal neovascularization was detected during the follow-up.

Results: Successful regression of retinal neovascularization was achieved after argon green laser panretinal photocoagulation in addition to oral steroid and salazopyrine.

Conclusion: Retinal vascular involvement is a rare ocular feature of Crohn's disease and may result in retinal neovascularization that may necessitate prompt laser photocoagulation.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Inflammatory Agents / therapeutic use
  • Crohn Disease / complications*
  • Diagnostic Techniques, Ophthalmological
  • Drug Combinations
  • Female
  • Fluorescein Angiography
  • Fundus Oculi
  • Glucosamine / analogs & derivatives*
  • Glucosamine / therapeutic use
  • Humans
  • Indocyanine Green
  • Laser Coagulation
  • Prednisolone / therapeutic use
  • Retinal Artery Occlusion / etiology*
  • Retinal Artery Occlusion / therapy
  • Retinal Neovascularization / etiology*
  • Retinal Neovascularization / therapy
  • Sulfasalazine / therapeutic use
  • Treatment Outcome
  • Vasculitis / etiology*
  • Vasculitis / therapy


  • Anti-Inflammatory Agents
  • Drug Combinations
  • Salazopyrine
  • Sulfasalazine
  • Prednisolone
  • Indocyanine Green
  • Glucosamine