A two-step conversion of alpha,beta-unsaturated ketones to their alpha-carbalkoxy or alpha-carbamoyl derivatives

Fabio E S Souza; Hamish S Sutherland; Rina Carlini; Russell Rodrigo

doi:10.1021/jo020081c

A two-step conversion of alpha,beta-unsaturated ketones to their alpha-carbalkoxy or alpha-carbamoyl derivatives

J Org Chem. 2002 Sep 6;67(18):6568-70. doi: 10.1021/jo020081c.

Authors

Fabio E S Souza¹, Hamish S Sutherland, Rina Carlini, Russell Rodrigo

Affiliation

¹ Guelph-Waterloo Centre for Chemistry and Biochemistry, Department of Chemistry, University of Waterloo, Waterloo, Ontario, Canada N2L 3G1.

PMID: 12201786
DOI: 10.1021/jo020081c

Abstract

Several enones are converted into their alpha-iodo derivatives in excellent yields and carbonylated with palladium catalysis in the presence of alcohol or amines to the alpha-carbonyl enones in satisfactory yields.